According to a report dated March 08, 2016, researchers at England’s Warwick University have discovered a new treatment for women who have experienced failed pregnancies.
They have discovered that thousands of women suffer from recurrent miscarriages owing to lack of stem cells in the lining of their womb. This report was published in the journal named ‘Stem Cells’.
Jan Brosens, the lead researcher stated that they discovered that lining of the uterus in patients with recurrent miscarriage is already defective before pregnancy.
He suggests that these defects can be corrected before patients try achieving another pregnancy. He further adds that this might be the only way of preventing miscarriages in such cases.
The study pointed out that around 15-20 percent of such pregnancies end up in miscarriage and one in 100 women who try conceiving, suffer from recurrent miscarriages.
Sometimes, they have to suffer from loss of 3 or more consecutive pregnancies. The researchers examined tissue samples of womb lining that were donated by 183 women and they found that an epigenetic signature was absent in cultures that were established from womb biopsies that were taken from women who suffered from recurrent miscarriages.
As compared to the control group of the study, fewer stem cells could be isolated from the womb’s lining of patients suffering from recurrent miscarriages. Researchers found that a stem cell shortage can accelerate cellular ageing in womb.
Brosens stated that cultured cells from women having undergone 3 or more consecutive miscarriages showed that ageing cells in the womb’s lining don’t have the ability of adequately preparing for pregnancy.
As this process is a fast one, researchers are not going to work on ways for increasing this renewing of stem cells in the womb lining.
New methods are going to be tested by the team for improving womb lining. Even an endometrial ‘scratch’ procedure would be explored for helping the embryos implant.